Raloxifene is a Female-specific Proteostasis Therapeutic in the Spinal Cord

Several neurodegenerative disorders are characterized by proteasome dysfunctions leading to protein aggregations and pathogenesis. Since we showed that estrogen receptor alpha (ERα) activates the proteasome, drugs able to stimulate ERα in the central nervous system (CNS) could hold potential for the...

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Detalles Bibliográficos
Autores principales: Jenkins, Edmund Charles, Casalena, Gabriella, Gomez, Maria, Zhao, Dazhi, Kenny, Timothy C, Shah, Nagma, Manfredi, Giovanni, Germain, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774777/
https://www.ncbi.nlm.nih.gov/pubmed/33269387
http://dx.doi.org/10.1210/endocr/bqaa221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774777/
https://www.ncbi.nlm.nih.gov/pubmed/33269387
http://dx.doi.org/10.1210/endocr/bqaa221

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