Genetic diversity of the Plasmodium falciparum GTP-cyclohydrolase 1, dihydrofolate reductase and dihydropteroate synthetase genes reveals new insights into sulfadoxine-pyrimethamine antimalarial drug resistance

Plasmodium falciparum parasites resistant to antimalarial treatments have hindered malaria disease control. Sulfadoxine-pyrimethamine (SP) was used globally as a first-line treatment for malaria after wide-spread resistance to chloroquine emerged and, although replaced by artemisinin combinations, i...

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Detalles Bibliográficos
Autores principales: Turkiewicz, Anna, Manko, Emilia, Sutherland, Colin J., Diez Benavente, Ernest, Campino, Susana, Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774857/
https://www.ncbi.nlm.nih.gov/pubmed/33382691
http://dx.doi.org/10.1371/journal.pgen.1009268

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