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Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube

Using the zebrafish neural tube as a model, we uncover the in vivo mechanisms allowing the generation of two opposing apical epithelial surfaces within the centre of an initially unpolarised, solid organ. We show that Mpp5a and Rab11a play a dual role in coordinating the generation of ipsilateral ju...

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Detalles Bibliográficos
Autores principales: Symonds, Andrew C., Buckley, Clare E., Williams, Charlotte A., Clarke, Jonathan D. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774892/
https://www.ncbi.nlm.nih.gov/pubmed/33361092
http://dx.doi.org/10.1242/dev.191494

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