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Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube
Using the zebrafish neural tube as a model, we uncover the in vivo mechanisms allowing the generation of two opposing apical epithelial surfaces within the centre of an initially unpolarised, solid organ. We show that Mpp5a and Rab11a play a dual role in coordinating the generation of ipsilateral ju...
Autores principales: | Symonds, Andrew C., Buckley, Clare E., Williams, Charlotte A., Clarke, Jonathan D. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774892/ https://www.ncbi.nlm.nih.gov/pubmed/33361092 http://dx.doi.org/10.1242/dev.191494 |
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