Risk-benefit analysis of isoniazid monotherapy to prevent tuberculosis in patients with rheumatic diseases exposed to prolonged, high-dose glucocorticoids

OBJECTIVE: To investigate the incidence of tuberculosis (TB) in patients with rheumatic diseases receiving high-dose glucocorticoids and to evaluate the preventive effect of isoniazid (INH). METHODS: This study included 1618 treatment episodes of prolonged (≥4 weeks), high-dose steroids (≥30mg/day o...

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Detalles Bibliográficos
Autores principales: Park, Jun Won, Curtis, Jeffrey R., Lee, Hajeong, Lee, Jung-Kyu, Song, Yeong Wook, Lee, Eun Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774985/
https://www.ncbi.nlm.nih.gov/pubmed/33382731
http://dx.doi.org/10.1371/journal.pone.0244239

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