A Study on the Clinical and Hormonal Profile of Polycystic Ovarian Syndrome Patients attending a Tertiary Care Hospital: A Descriptive Cross-sectional Study

INTRODUCTION: Polycystic ovarian syndrome is the most common endocrinological disorder in women of reproductive age and has a considerable metabolic, reproductive, and cardiovascular consequences. This study was designed to provide an overview of the clinical profile and hormonal presentation of the patients with polycystic ovarian syndrome attending a tertiary care hospital. METHODS: A descriptive cross-sectional study was conducted between September 14, 2019 to October 16, 2019 on patients presenting to a tertiary care hospital, after obtaining ethical clearance from Institutional Review Committee (Dated 03/09/2019) and informed consent from the patient or patient relatives. Data entry and analysis were done in Microsoft Excel 10. The data was statistically analysed using Statistical Package for the Social Sciences version 20.0. RESULTS: Out of 100 patients, the mean age of the patients was 24.9 ± 4.52 years, and the most common group was 26-34 years. The most common presenting symptom was menstrual irregularity which was seen in 86 (86%) of the patients, followed by weight gain in 55 (55%) of the patients. Thirty (30%) patients were overweight, while 11 (11%) of the patients had grade I obesity. LH/FSH ratio was more than or equal to 2 in eighty-three percent 83 (83%) of the patients. CONCLUSIONS: Polycystic ovarian syndrome has varying clinical manifestations, most commonly affecting the young women of reproductive age group. The commonest presenting complaint in our study was menstrual abnormality. Majority of the patients had a deranged hormonal profile which can increase the risk of cardiovascular diseases and type two diabetes. Thus, awareness regarding the disease is important for early diagnosis prevention of complications.