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Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital

INTRODUCTION: The prevalence of allergic rhinitis has increased significantly globally over the last two decades. Detection of sensitizing aeroallergens plays a crucial role in the diagnosis and management of this troublesome disease. This study aims to investigate the spectrum of aeroallergens sens...

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Autores principales: Pokharel, Monika, Shrestha, Bikash Lal, Karn, Dharmendra, Dhakal, Ashish, K.C., Abha Kiran, Shrestha, Krishna Sundar, Shakya, Sushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775014/
https://www.ncbi.nlm.nih.gov/pubmed/34506424
http://dx.doi.org/10.31729/jnma.5218
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author Pokharel, Monika
Shrestha, Bikash Lal
Karn, Dharmendra
Dhakal, Ashish
K.C., Abha Kiran
Shrestha, Krishna Sundar
Shakya, Sushan
author_facet Pokharel, Monika
Shrestha, Bikash Lal
Karn, Dharmendra
Dhakal, Ashish
K.C., Abha Kiran
Shrestha, Krishna Sundar
Shakya, Sushan
author_sort Pokharel, Monika
collection PubMed
description INTRODUCTION: The prevalence of allergic rhinitis has increased significantly globally over the last two decades. Detection of sensitizing aeroallergens plays a crucial role in the diagnosis and management of this troublesome disease. This study aims to investigate the spectrum of aeroallergens sensitization in patients with allergic rhinitis in a tertiary care hospital. METHODS: A descriptive cross-sectional study conducted in the Department of Otorhinolaryngology of our hospital between January 2016 to December 2019. Ethical approval was taken from the Institutional Review Committee (No: 210/19). Patients diagnosed with allergic rhinitis were enrolled using the convenience sampling technique. Data entry and analysis was done using IBM Statistical Package for Social Sciences version 20.0. RESULTS: Among 170 patients, altogether 103 (60.6%) patients yielded positive responses on the skin prick test. The most prevalent aeroallergens were Lepidoglyphus 86 (50.60%), Dermatophagoides pteronyssinus 85 (50%), Dermatophagoides farina 82 (48.20%), Thyrophagus 50 (29.40%), Blomia 46 (27.10%), Acarus 43 (25.30%), cat dander 26 (15.30%), dog dander 24 (14.10%), cow and buffalo dander 20 (11.8%), ragweed 20 (11.8%), grass pollen 18 (10.60%) and mugwort 17 (10%). CONCLUSIONS: This study highlights that the frequency of aeroallergens based on skin prick test in patients presenting to a tertiary care hospital which showed the dominance of house dust mites, dog and cat hair, pollen, and grasses. Reduced exposure and training of patients about protection against these agents will possibly help in controlling the severity of allergic rhinitis in this region.
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spelling pubmed-77750142021-01-05 Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital Pokharel, Monika Shrestha, Bikash Lal Karn, Dharmendra Dhakal, Ashish K.C., Abha Kiran Shrestha, Krishna Sundar Shakya, Sushan JNMA J Nepal Med Assoc Original Article INTRODUCTION: The prevalence of allergic rhinitis has increased significantly globally over the last two decades. Detection of sensitizing aeroallergens plays a crucial role in the diagnosis and management of this troublesome disease. This study aims to investigate the spectrum of aeroallergens sensitization in patients with allergic rhinitis in a tertiary care hospital. METHODS: A descriptive cross-sectional study conducted in the Department of Otorhinolaryngology of our hospital between January 2016 to December 2019. Ethical approval was taken from the Institutional Review Committee (No: 210/19). Patients diagnosed with allergic rhinitis were enrolled using the convenience sampling technique. Data entry and analysis was done using IBM Statistical Package for Social Sciences version 20.0. RESULTS: Among 170 patients, altogether 103 (60.6%) patients yielded positive responses on the skin prick test. The most prevalent aeroallergens were Lepidoglyphus 86 (50.60%), Dermatophagoides pteronyssinus 85 (50%), Dermatophagoides farina 82 (48.20%), Thyrophagus 50 (29.40%), Blomia 46 (27.10%), Acarus 43 (25.30%), cat dander 26 (15.30%), dog dander 24 (14.10%), cow and buffalo dander 20 (11.8%), ragweed 20 (11.8%), grass pollen 18 (10.60%) and mugwort 17 (10%). CONCLUSIONS: This study highlights that the frequency of aeroallergens based on skin prick test in patients presenting to a tertiary care hospital which showed the dominance of house dust mites, dog and cat hair, pollen, and grasses. Reduced exposure and training of patients about protection against these agents will possibly help in controlling the severity of allergic rhinitis in this region. Journal of the Nepal Medical Association 2020-11 2020-11-30 /pmc/articles/PMC7775014/ /pubmed/34506424 http://dx.doi.org/10.31729/jnma.5218 Text en © The Author(s) 2018. http://creativecommons.org/licenses/by/4.0/ This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Pokharel, Monika
Shrestha, Bikash Lal
Karn, Dharmendra
Dhakal, Ashish
K.C., Abha Kiran
Shrestha, Krishna Sundar
Shakya, Sushan
Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital
title Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital
title_full Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital
title_fullStr Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital
title_full_unstemmed Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital
title_short Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital
title_sort prevalence of aeroallergens in allergic rhinitis in a tertiary care hospital
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775014/
https://www.ncbi.nlm.nih.gov/pubmed/34506424
http://dx.doi.org/10.31729/jnma.5218
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