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Decreased sensitivity to the anorectic effects of leptin in mice that lack a Pomc-specific neural enhancer
Enhancer redundancy has been postulated to provide a buffer for gene expression against genetic and environmental perturbations. While work in Drosophila has identified functionally overlapping enhancers, work in mammalian models has been limited. Recently, we have identified two partially redundant...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775064/ https://www.ncbi.nlm.nih.gov/pubmed/33382813 http://dx.doi.org/10.1371/journal.pone.0244793 |