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B7-H3-Induced Signaling in Lung Adenocarcinoma Cell Lines with Divergent Epidermal Growth Factor Receptor Mutation Patterns

The cosignal molecule B7-H3 is gaining attention due to its abnormal expression and abundant signal transduction in many types of malignancies. B7-H3-induced signaling includes at least three cascades: PI3K/AKT, JAK2/STAT3, and Raf/MEK/ERK1/2, which are also involved in epidermal growth factor recep...

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Detalles Bibliográficos
Autores principales:	Ding, Meng, Liao, Haixiu, Zhou, Nannan, Yang, Ying, Guan, Shihe, Chen, Liwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775133/ https://www.ncbi.nlm.nih.gov/pubmed/33426073 http://dx.doi.org/10.1155/2020/8824805

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