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Area under the Curve-Based Dosing of Vancomycin in Critically Ill Patients Using 6-Hour Urine Creatinine Clearance Measurement

BACKGROUND: The area under the curve- (AUC-) guided vancomycin dosing is the best strategy for individualized therapy in critical illnesses. Since AUC can be calculated directly using drug clearance (CL(van)), any parameter estimating CL(van) will be able to achieve the goal of 24-hour AUC (AUC(24 h...

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Detalles Bibliográficos
Autores principales: Shahrami, Bita, Najmeddin, Farhad, Ghaffari, Saeideh, Najafi, Atabak, Rouini, Mohammad Reza, Mojtahedzadeh, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775160/
https://www.ncbi.nlm.nih.gov/pubmed/33425384
http://dx.doi.org/10.1155/2020/8831138