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Mechanical force-driven TNFα endocytosis governs stem cell homeostasis

Mesenchymal stem cells (MSCs) closely interact with the immune system, and they are known to secrete inflammatory cytokines in response to stress stimuli. The biological function of MSC-derived inflammatory cytokines remains elusive. Here, we reveal that even under physiological conditions, MSCs pro...

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Detalles Bibliográficos
Autores principales: Yu, Wenjing, Chen, Chider, Kou, Xiaoxing, Sui, Bingdong, Yu, Tingting, Liu, Dawei, Wang, Runci, Wang, Jun, Shi, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775432/
https://www.ncbi.nlm.nih.gov/pubmed/33384406
http://dx.doi.org/10.1038/s41413-020-00117-x

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