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Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP
Chronic inflammation is thought to contribute to the early pathogenesis of Alzheimer's disease (AD). However, the precise mechanism by which inflammatory cytokines promote the formation and deposition of Aβ remains unclear. Available data suggest that applications of inflammatory cytokines onto...
Autores principales: | Li, Zhigang, Moniruzzaman, Mohammed, Dastgheyb, Raha M., Yoo, Seung‐Wan, Wang, Meina, Hao, Hongbo, Liu, Jia, Casaccia, Patrizia, Nogueras‐Ortiz, Carlos, Kapogiannis, Dimitrios, Slusher, Barbara S., Haughey, Norman J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775567/ https://www.ncbi.nlm.nih.gov/pubmed/33408815 http://dx.doi.org/10.1002/jev2.12035 |
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