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Potential natural inhibitors of xanthine oxidase and HMG-CoA reductase in cholesterol regulation: in silico analysis

BACKGROUND: Hypercholesterolemia has posed a serious threat of heart diseases and stroke worldwide. Xanthine oxidase (XO), the rate-limiting enzyme in uric acid biosynthesis, is regarded as the root of reactive oxygen species (ROS) that generate atherosclerosis and cholesterol crystals. β-Hydroxy β-...

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Detalles Bibliográficos
Autores principales:	Marahatha, Rishab, Basnet, Saroj, Bhattarai, Bibek Raj, Budhathoki, Prakriti, Aryal, Babita, Adhikari, Bikash, Lamichhane, Ganesh, Poudel, Darbin Kumar, Parajuli, Niranjan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775628/ https://www.ncbi.nlm.nih.gov/pubmed/33386071 http://dx.doi.org/10.1186/s12906-020-03162-5

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