Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

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Severe-acute-respiratory-syndrome-related coronavirus 2 (SARS-CoV-2) is the positive-sense RNA virus that causes coronavirus disease 2019 (COVID-19). The genome of SARS-CoV-2 is unique among viral RNAs in its vast potential to form RNA structures, yet as much as 97% of its 30 kilobases have not been...

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Detalles Bibliográficos
Autores principales: Huston, Nicholas C., Wan, Han, Strine, Madison S., de Cesaris Araujo Tavares, Rafael, Wilen, Craig B., Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775661/
https://www.ncbi.nlm.nih.gov/pubmed/33444546
http://dx.doi.org/10.1016/j.molcel.2020.12.041
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