BBB pathophysiology–independent delivery of siRNA in traumatic brain injury

Small interfering RNA (siRNA)–based therapeutics can mitigate the long-term sequelae of traumatic brain injury (TBI) but suffer from poor permeability across the blood-brain barrier (BBB). One approach to overcoming this challenge involves treatment administration while BBB is transiently breached a...

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Detalles Bibliográficos
Autores principales: Li, Wen, Qiu, Jianhua, Li, Xiang-Ling, Aday, Sezin, Zhang, Jingdong, Conley, Grace, Xu, Jun, Joseph, John, Lan, Haoyue, Langer, Robert, Mannix, Rebekah, Karp, Jeffrey M., Joshi, Nitin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775748/
https://www.ncbi.nlm.nih.gov/pubmed/33523853
http://dx.doi.org/10.1126/sciadv.abd6889

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