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Abnormal neocortex arealization and Sotos-like syndrome–associated behavior in Setd2 mutant mice
Proper formation of area identities of the cerebral cortex is crucial for cognitive functions and social behaviors of the brain. It remains largely unknown whether epigenetic mechanisms, including histone methylation, regulate cortical arealization. Here, we removed SETD2, the methyltransferase for...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775761/ https://www.ncbi.nlm.nih.gov/pubmed/33523829 http://dx.doi.org/10.1126/sciadv.aba1180 |