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Horizontal genome transfer by cell-to-cell travel of whole organelles

Recent work has revealed that both plants and animals transfer genomes between cells. In plants, horizontal transfer of entire plastid, mitochondrial, or nuclear genomes between species generates new combinations of nuclear and organellar genomes, or produces novel species that are allopolyploid. Th...

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Detalles Bibliográficos
Autores principales: Hertle, Alexander P., Haberl, Benedikt, Bock, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775762/
https://www.ncbi.nlm.nih.gov/pubmed/33523859
http://dx.doi.org/10.1126/sciadv.abd8215
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author Hertle, Alexander P.
Haberl, Benedikt
Bock, Ralph
author_facet Hertle, Alexander P.
Haberl, Benedikt
Bock, Ralph
author_sort Hertle, Alexander P.
collection PubMed
description Recent work has revealed that both plants and animals transfer genomes between cells. In plants, horizontal transfer of entire plastid, mitochondrial, or nuclear genomes between species generates new combinations of nuclear and organellar genomes, or produces novel species that are allopolyploid. The mechanisms of genome transfer between cells are unknown. Here, we used grafting to identify the mechanisms involved in plastid genome transfer from plant to plant. We show that during proliferation of wound-induced callus, plastids dedifferentiate into small, highly motile, amoeboid organelles. Simultaneously, new intercellular connections emerge by localized cell wall disintegration, forming connective pores through which amoeboid plastids move into neighboring cells. Our work uncovers a pathway of organelle movement from cell to cell and provides a mechanistic framework for horizontal genome transfer.
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spelling pubmed-77757622021-01-14 Horizontal genome transfer by cell-to-cell travel of whole organelles Hertle, Alexander P. Haberl, Benedikt Bock, Ralph Sci Adv Research Articles Recent work has revealed that both plants and animals transfer genomes between cells. In plants, horizontal transfer of entire plastid, mitochondrial, or nuclear genomes between species generates new combinations of nuclear and organellar genomes, or produces novel species that are allopolyploid. The mechanisms of genome transfer between cells are unknown. Here, we used grafting to identify the mechanisms involved in plastid genome transfer from plant to plant. We show that during proliferation of wound-induced callus, plastids dedifferentiate into small, highly motile, amoeboid organelles. Simultaneously, new intercellular connections emerge by localized cell wall disintegration, forming connective pores through which amoeboid plastids move into neighboring cells. Our work uncovers a pathway of organelle movement from cell to cell and provides a mechanistic framework for horizontal genome transfer. American Association for the Advancement of Science 2021-01-01 /pmc/articles/PMC7775762/ /pubmed/33523859 http://dx.doi.org/10.1126/sciadv.abd8215 Text en Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Hertle, Alexander P.
Haberl, Benedikt
Bock, Ralph
Horizontal genome transfer by cell-to-cell travel of whole organelles
title Horizontal genome transfer by cell-to-cell travel of whole organelles
title_full Horizontal genome transfer by cell-to-cell travel of whole organelles
title_fullStr Horizontal genome transfer by cell-to-cell travel of whole organelles
title_full_unstemmed Horizontal genome transfer by cell-to-cell travel of whole organelles
title_short Horizontal genome transfer by cell-to-cell travel of whole organelles
title_sort horizontal genome transfer by cell-to-cell travel of whole organelles
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775762/
https://www.ncbi.nlm.nih.gov/pubmed/33523859
http://dx.doi.org/10.1126/sciadv.abd8215
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