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Heteromultivalent topology-matched nanostructures as potent and broad-spectrum influenza A virus inhibitors
Here, we report the topology-matched design of heteromultivalent nanostructures as potent and broad-spectrum virus entry inhibitors based on the host cell membrane. Initially, we investigate the virus binding dynamics to validate the better binding performance of the heteromultivalent moieties as co...
Autores principales: | Nie, Chuanxiong, Stadtmüller, Marlena, Parshad, Badri, Wallert, Matthias, Ahmadi, Vahid, Kerkhoff, Yannic, Bhatia, Sumati, Block, Stephan, Cheng, Chong, Wolff, Thorsten, Haag, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775783/ https://www.ncbi.nlm.nih.gov/pubmed/33523846 http://dx.doi.org/10.1126/sciadv.abd3803 |
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