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In vivo delivery of a multiepitope peptide and Nef protein using novel cell-penetrating peptides for development of HIV-1 vaccine candidate
OBJECTIVES: A potent HIV vaccine should overcome some limitations such as polymorphism of human HLA, the diversity of HIV-1 virus, and the lack of an effective delivery system. In this study, a DNA construct encoding Nef(60–84), Nef(126–144), Vpr(34–47), Vpr(60–75), Gp160(30–53), Gp160(308–323,) and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775797/ https://www.ncbi.nlm.nih.gov/pubmed/33386500 http://dx.doi.org/10.1007/s10529-020-03060-3 |