Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction

An inflammatory response is required for tissue healing after a myocardial infarction (MI), but the process must be balanced to prevent maladaptive remodeling. This study shows that improved survival and cardiac function following MI, in mice deficient for the NLRP3 inflammasome, can be recapitulate...

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Detalles Bibliográficos
Autores principales: Louwe, Mieke C., Olsen, Maria B., Kaasbøll, Ole J., Yang, Kuan, Fosshaug, Linn E., Alfsnes, Katrine, Øgaard, Jonas D.S., Rashidi, Azita, Skulberg, Vidar M., Yang, Mingyi, de Miranda Fonseca, Davi, Sharma, Animesh, Aronsen, Jan Magnus, Schrumpf, Elisabeth, Ahmed, Muhammad Shakil, Dahl, Christen Peder, Nyman, Tuula A., Ueland, Thor, Melum, Espen, Halvorsen, Bente E., Bjørås, Magnar, Attramadal, Håvard, Sjaastad, Ivar, Aukrust, Pål, Yndestad, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775960/
https://www.ncbi.nlm.nih.gov/pubmed/33426377
http://dx.doi.org/10.1016/j.jacbts.2020.09.013

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