33. Intranasal M2SR (M2-deficient Single Replication) Live H3N2 Influenza Investigational Vaccine Induces Serum HAI & Broad Immune Responses in High Proportion of Adults

BACKGROUND: A single intranasal (IN) dose of 10(8) TCID(50) M2SR protected a responder subset of adults against infection and disease in a prior human influenza challenge study (EudraCT number: 2017-004971-30). Higher dose levels of M2SR were assessed in this phase 1b study to enhance immune respons...

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Detalles Bibliográficos
Autores principales: Eiden, Joseph, Ellis, Ruth, Fierro, Carlos, Schwartz, Howard, Adams, Mark, Ellis, Kimberly, Aitchison, Roger, Herber, Renee, Bilsel, Pamuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776045/
http://dx.doi.org/10.1093/ofid/ofaa439.078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776045/
http://dx.doi.org/10.1093/ofid/ofaa439.078

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