Cargando…

159. efficacy of CD377, a Novel Antiviral Fc-conjugate, Against Seasonal Influenza in Lethal Mouse Infection Models

BACKGROUND: Cidara’s AVCs (antiviral Fc-conjugates) are novel conjugates of potent, antiviral agents with the Fc domain of human IgG1. CD377 is an AVC development candidate for prevention and treatment of influenza that has broad anti-neuraminidase activity in both enzymatic and cell-based assays an...

Descripción completa

Detalles Bibliográficos
Autores principales: Levin, James, Amundson, Karin, Shathia, Kim, Borchardt, Allen, Lam, Thanh, Brady, Tom, Noncovich, Alain, Tari, Les
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776175/
http://dx.doi.org/10.1093/ofid/ofaa439.469