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159. efficacy of CD377, a Novel Antiviral Fc-conjugate, Against Seasonal Influenza in Lethal Mouse Infection Models
BACKGROUND: Cidara’s AVCs (antiviral Fc-conjugates) are novel conjugates of potent, antiviral agents with the Fc domain of human IgG1. CD377 is an AVC development candidate for prevention and treatment of influenza that has broad anti-neuraminidase activity in both enzymatic and cell-based assays an...
Autores principales: | Levin, James, Amundson, Karin, Shathia, Kim, Borchardt, Allen, Lam, Thanh, Brady, Tom, Noncovich, Alain, Tari, Les |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776175/ http://dx.doi.org/10.1093/ofid/ofaa439.469 |
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