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Preclinical development of a humanized chimeric antigen receptor against B-cell maturation antigen for multiple myeloma

Multiple myeloma is a prevalent and incurable disease, despite the development of new and effective drugs. The recent development of chimeric antigen receptor (CAR)T cells has shown impressive results in the treatment of patients with relapsed or refractory hematologic B-cell malignancies. In recent...

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Detalles Bibliográficos
Autores principales: Perez-Amill, Lorena, Suñe, Guillermo, Antoñana-Vildosola, Asier, Castella, Maria, Najjar, Amer, Bonet, Jaume, Fernández-Fuentes, Narcis, Inogés, Susana, López, Ascensión, Bueno, Clara, Juan, Manel, Urbano-Ispizua, Alvaro, Martín-Antonio, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776337/
https://www.ncbi.nlm.nih.gov/pubmed/31919085
http://dx.doi.org/10.3324/haematol.2019.228577