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Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukemia

Retrotransposons such as LINE-1 and Alu comprise >25% of the human genome. While global hypomethylation of these elements has been widely reported in solid tumours, their epigenetic dysregulation is yet to be characterised in chronic lymphocytic leukemia (CLL), and there has been scant considerat...

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Detalles Bibliográficos
Autores principales:	Barrow, Timothy M., Doo, Nicole Wong, Milne, Roger L., Giles, Graham G., Willmore, Elaine, Strathdee, Gordon, Byun, Hyang-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776340/ https://www.ncbi.nlm.nih.gov/pubmed/31919093 http://dx.doi.org/10.3324/haematol.2019.228478

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