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196. Antibodies to Vaccine-preventable Infections After CAR-T Cell Immunotherapy for B Cell Malignancies

BACKGROUND: Chimeric antigen receptor-modified T (CAR-T) cell immunotherapy for B cell hematologic malignancies results in prolonged B cell depletion. Little is known about the effects of CAR-T cell therapy on pre-existing pathogen-specific humoral immunity. METHODS: We conducted a prospective, cros...

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Detalles Bibliográficos
Autores principales: Walti, Carla S, Maalouf, Joyce, Boonyaratanakornkit, Jim, Keane-Candib, Jacob, Taylor, Justin J, Hirayama, Alexandre V, Bar, Merav, Gardner, Rebecca A, Green, Damian J, Boeckh, Michael, Maloney, David G, Krantz, Elizabeth M, Turtle, Cameron J, Hill, Joshua A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776444/
http://dx.doi.org/10.1093/ofid/ofaa439.506