1272. Efficacy of a Non-Peptide, Small Molecule Mimic of Host Defense Proteins in Mouse Models of Disseminated Candidiasis and Aspergillosis

BACKGROUND: We are developing a series of small nonpeptide mimics of host defense proteins (smHDPs) for antifungal applications. MICs < 0.1 µg/ ml have been demonstrated against multiple yeast and mold species. Their potential therapeutic utility has been evaluated in animal models of disseminate...

Descripción completa

Detalles Bibliográficos
Autores principales: Scott, Richard W, Baugh, Simon D P, Freeman, Katie B, Weaver, Damian G, Chaly, Anna L, Whitman, David B, Thanna, Sandeep, Diamond, Gill, Nguyen, Phung, Deviney, Ashley, Weiss, William J, Pulse, Mark E, Reitz, Allen B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776474/
http://dx.doi.org/10.1093/ofid/ofaa439.1456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776474/
http://dx.doi.org/10.1093/ofid/ofaa439.1456

Ejemplares similares