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1445. Deciphering the Role of the Y221H Ω-loop Substitution in Pseudomonas-derived Cephalosporinase (PDC) in Cephalosporin Resistance
BACKGROUND: Antimicrobial resistance is a major global health threat. Pseudomonas aeruginosa is a leading cause of nosocomial infections and a key opportunistic pathogen in cystic fibrosis. Multidrug resistant strains are classified as a “serious threat” by the CDC. Pseudomonas-derived cephalosporin...
Autores principales: | Mack, Andrew R, Barnes, Melissa D, Taracila, Magdalena A, Mojica, Maria F, Kumar, Vijay, Rutter, Joseph, van den Akker, Focco, Page, Malcolm, Haider, Shozeb, Bonomo, Robert A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776846/ http://dx.doi.org/10.1093/ofid/ofaa439.1626 |
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