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1207. Combining standard bacterial vaginosis treatment with cystine uptake inhibitors to block growth of Lactobacillus iners is a potential a target for shifting the cervicovaginal microbiota towards health-associated Lactobacillus crispatus-dominant communities
BACKGROUND: Cervicovaginal microbiota domination by Lactobacillus crispatus is associated with beneficial health outcomes, whereas L. iners dominance has more adverse associations. However bacterial vaginosis (BV) treatment with metronidazole (MTZ) typically leads to domination by L. iners rather th...
Autores principales: | Bloom, Seth M, Mafunda, Nomfuneko A, Woolston, Benjamin M, Hayward, Matthew R, Frempong, Josephine F, Xu, Jiawu, Mitchell, Alissa, Westergaard, Xavier, Rice, Justin K, Choksi, Namit, Balskus, Emily P, Mitchell, Caroline M, Kwon, Douglas S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777507/ http://dx.doi.org/10.1093/ofid/ofaa439.1392 |
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