Cargando…
1275. Evaluation of in vitro activity of manogepix against multidrug-resistant and pan-resistant Candida auris from the New York Outbreak
BACKGROUND: An ongoing Candida auris outbreak in the New York metropolitan area is the largest recorded to date in North America. NY C. auris isolates demonstrate resistance to fluconazole and variable resistance to other antifungals. Thus, there is an urgent need for new drugs with a novel mechanis...
Autores principales: | Zhu, Yan Chun, Kilburn, Shannon N, Kapoor, Mili, Chaturvedi, Sudha, Shaw, Karen J, Chaturvedi, Vishnu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777565/ http://dx.doi.org/10.1093/ofid/ofaa439.1459 |
Ejemplares similares
-
1579. Multidrug-Resistant Candida auris Isolates From New York Hospitals and Healthcare Facilities Are Susceptible to Antifungal Combinations
por: O’Brien, Brittany, et al.
Publicado: (2019) -
Evaluation of Resistance Development to the Gwt1 Inhibitor Manogepix (APX001A) in Candida Species
por: Kapoor, Mili, et al.
Publicado: (2019) -
Candida auris: From Multidrug Resistance to Pan-Resistant Strains
por: Ademe, Muluneh, et al.
Publicado: (2020) -
Candida auris Isolates Resistant to Three Classes of Antifungal Medications — New York, 2019
por: Ostrowsky, Belinda, et al.
Publicado: (2020) -
Enhanced Efflux Pump Expression in Candida Mutants Results in Decreased Manogepix Susceptibility
por: Liston, Sean D., et al.
Publicado: (2020)