168. Efficacy of the Novel gwt1 Inhibitor APX2039 in a Rabbit Model of cryptococcus Meningitis

BACKGROUND: Cryptococcal meningitis (CM), caused primarily by Cryptococcus neoformans, is uniformly fatal if not treated. Treatment options are limited especially in resource-poor geographical regions, and mortality rates remain high despite current therapies. New oral treatment options are needed t...

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Detalles Bibliográficos
Autores principales: Shaw, Karen J, Giamberardino, Charles D, Soltow, Quinlyn A, Tenor, Jennifer, Toffaletti, Dena, Boua, Jane-Valeriane, Marius, Choiselle, Palmucci, Julia R, Perfect, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777792/
http://dx.doi.org/10.1093/ofid/ofaa439.478

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