Cargando…

664. LiaX as a Surrogate Marker of Daptomycin Susceptibility in Multidrug-Resistant Enterococcus faecium Recovered from Cancer Patients

BACKGROUND: Vancomycin-resistant Enterococcus faecium (VREfm) are leading causes of bloodstream infections (BSI) in patients (pts) with hematological malignancies (HM). Daptomycin (DAP) is commonly used to treat VRE BSI, but DAP non-susceptibility (DAP-NS) in pts with HM is increasing. Current metho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Axell-House, Dierdre B, Khan, Ayesha, Shamoo, Yousif, Shelburne, Samuel A, Tran, Truc T, Arias, Cesar A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Poster Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777827/ http://dx.doi.org/10.1093/ofid/ofaa439.857

Ejemplares similares

2350. LiaF is required for LiaX mediated protection against Daptomycin and LL-37 in Enterococcus faecalis OG1RF
por: Botero, Diana Panesso, et al.
Publicado: (2022)

599. LiaF is an Activator of the LiaR-Mediated Response Against Daptomycin and Antimicrobial Peptides in Multidrug-Resistant Enterococcus faecalis (Efs)
por: Ortiz-Velez, Laura C, et al.
Publicado: (2019)

The LiaFSR-LiaX System Mediates Resistance of Enterococcus faecium to Peptide Antibiotics and to Aureocin A53- and Enterocin L50-Like Bacteriocins
por: Tymoszewska, Aleksandra, et al.
Publicado: (2023)

1399. Efficacy of Daptomycin Combination with β-Lactams for Daptomycin-resistant Enterococcus faecium Harboring LiaSR Substitutions
por: Kebriaei, Razieh, et al.
Publicado: (2018)

602. Mechanism of LiaY-Mediated Daptomycin Resistance in Enterococcus faecalis
por: Nguyen, April, et al.
Publicado: (2019)

Genomic Pathways Associated with Daptomycin (DAP) Resistance in DAP-Susceptible Enterococcus faecium Harboring Substitutions in LiaFSR
por: Tran, Truc T, et al.
Publicado: (2017)

1521. Non-faecium Non-faecalis enterococcal bloodstream infections in patients with cancer
por: Axell-House, Dierdre B, et al.
Publicado: (2022)

1546. Efficacy of Daptomycin Combinations Against Daptomycin-Resistant Enterococcus faecium Differs by β-lactam
por: Kebriaei, Razieh, et al.
Publicado: (2019)

Enolpyruvate transferase MurAA(A149E), identified during adaptation of Enterococcus faecium to daptomycin, increases stability of MurAA–MurG interaction
por: Zhou, Yue, et al.
Publicado: (2023)

601. TelA and XpaC Are Novel Mediators of Daptomycin Resistance in Enterococcus faecium
por: Tran, Truc T, et al.
Publicado: (2019)

A Whole Genome Sequencing (WGS) Approach to Predict Daptomycin (DAP) Susceptibility of Enterococcus faecium
por: Contreras, German, et al.
Publicado: (2017)

1275. Dynamics of Enterococcus faecalis Cardiolipin Synthase Gene Expression Reveal Compensatory Roles in Daptomycin Resistance
por: Nguyen, April, et al.
Publicado: (2021)

A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin
por: Davlieva, Milya, et al.
Publicado: (2015)

1573. Daptomycin Resistant Enterococcus faecium: Combination Therapy Screening
por: Kebriaei, Razieh, et al.
Publicado: (2020)

2176. Cardiolipin Synthases Play Redundant Roles And Are Required for Membrane Remodeling in Daptomycin Resistant Enterococcus faecalis
por: Nguyen, April, et al.
Publicado: (2023)

The LiaFSR and BsrXRS Systems Contribute to Bile Salt Resistance in Enterococcus faecium Isolates
por: Zhou, Luoxiong, et al.
Publicado: (2019)

Phage-Antibiotic Cocktail Rescues Daptomycin and Phage Susceptibility against Daptomycin-Nonsusceptible Enterococcus faecium in a Simulated Endocardial Vegetation Ex Vivo Model
por: Kunz Coyne, Ashlan J., et al.
Publicado: (2023)

Acquisition of Daptomycin Resistance by Enterococcus faecium Confers Collateral Sensitivity to Glycopeptides
por: Zeng, Weiliang, et al.
Publicado: (2022)

Intrathecal daptomycin use in a challenging case of Enterococcus faecium ventriculitis
por: Dhariwal, Ankush, et al.
Publicado: (2022)

Daptomycin-Resistant Enterococcus faecalis Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Membrane Phospholipids
por: Tran, Truc T., et al.
Publicado: (2013)

New Mutations in cls Lead to Daptomycin Resistance in a Clinical Vancomycin- and Daptomycin-Resistant Enterococcus faecium Strain
por: Li, Weiwei, et al.
Publicado: (2022)

Small RNAs in vancomycin-resistant Enterococcus faecium involved in daptomycin response and resistance
por: Sinel, Clara, et al.
Publicado: (2017)

Daptomycin versus Glycopeptides for the Treatment of Enterococcus faecium Bacteraemia: A Cohort Study
por: Echeverría-Esnal, Daniel, et al.
Publicado: (2021)

Daptomycin Resistance in Enterococci Is Associated with Distinct Alterations of Cell Membrane Phospholipid Content
por: Mishra, Nagendra N., et al.
Publicado: (2012)

Breakthrough daptomycin-, linezolid-, vancomycin-resistant Enterococcus faecium bacteremia during protracted daptomycin therapy: A case report
por: Pincus, Nathan B., et al.
Publicado: (2022)

2182. Expression of the MadR regulon in Enterococcus faecalis OG117 is influenced by the presence of the LiaS Histidine Kinase of the LiaFSR pathway
por: Rizvi, Samie A, et al.
Publicado: (2023)

Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium
por: Kinnear, Clare L., et al.
Publicado: (2020)

In vitro activities of thiazolidione derivatives combined with daptomycin against clinical Enterococcus faecium strains
por: Chen, Zhong, et al.
Publicado: (2022)

903. Resensitization to β-Lactams in Enterococci Depends on Penicillin-Binding Protein (PBP) Mislocalization and Is Mediated by a Single Protein That Modulates Cell Membrane (CM) Adaptation to Daptomycin (DAP)
por: Khan, Ayesha, et al.
Publicado: (2019)

Phage Cocktails with Daptomycin and Ampicillin Eradicates Biofilm-Embedded Multidrug-Resistant Enterococcus faecium with Preserved Phage Susceptibility
por: Coyne, Ashlan J. Kunz, et al.
Publicado: (2022)

Reduced Chlorhexidine and Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium after Serial Chlorhexidine Exposure
por: Bhardwaj, Pooja, et al.
Publicado: (2017)

478 Daptomycin Susceptible vs Nonsusceptible Enterococcus faecium Bacteremias: Comparison of Clinical and Microbiological Outcomes
por: Lee, Spencer, et al.
Publicado: (2014)

1019. Treatment Outcomes for Enterococcus faecium Bacteremia in Solid-Organ Transplant Patients: Implications for Daptomycin
por: Mercuro, Nicholas J, et al.
Publicado: (2018)

Evolution and mutations predisposing to daptomycin resistance in vancomycin-resistant Enterococcus faecium ST736 strains
por: Wang, Guiqing, et al.
Publicado: (2018)

1446. Dynamics of Enterococcus faecalis Cardiolipin Synthase Gene Expression Reveal Compensatory Roles in Daptomycin Resistance
por: Nguyen, April, et al.
Publicado: (2020)

Emergence of a daptomycin-non-susceptible Enterococcus faecium strain that encodes mutations in DNA repair genes after high-dose daptomycin therapy
por: Matono, Takashi, et al.
Publicado: (2016)

A retrospective clinical comparison of daptomycin vs daptomycin and a beta-lactam antibiotic for treating vancomycin-resistant Enterococcus faecium bloodstream infections
por: Chuang, Yu-Chung, et al.
Publicado: (2018)

Genetic Basis of Emerging Vancomycin, Linezolid, and Daptomycin Heteroresistance in a Case of Persistent Enterococcus faecium Bacteremia
por: Chacko, Kieran I., et al.
Publicado: (2018)

Low phosphatase activity of LiaS and strong LiaR-DNA affinity explain the unusual LiaS to LiaR in vivo stoichiometry
por: Jani, Shailee, et al.
Publicado: (2020)

Daptomycin for a complicated urinary tract infection with vancomycin-resistant Enterococcus faecium in a renal transplant recipient
por: Eden, Gabriele, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jqe3rv8at9ct0ssv1b5idaa977