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1703. Hematologic Toxicity of Valganciclovir Prophylaxis in Solid Organ Transplant Recipients as a Function of Weight-adjusted Ganciclovir Exposure

BACKGROUND: Valganciclovir (VGC), an oral prodrug of ganciclovir (GCV), is 60% bioavailable. Manufacturer-recommended doses are adjusted for creatinine clearance (CrCl), but not weight (wt), while GCV doses are adjusted for CrCl and wt. Patients exposed to excess GCV by not wt-adjusting VGC doses ma...

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Detalles Bibliográficos
Autores principales:	Campanella, Toni A, Roy, Amanda, Gintjee, Thomas J, Donnelley, Monica, MacDougall, Conan, Gallagher, Jason C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Poster Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777869/ http://dx.doi.org/10.1093/ofid/ofaa439.1881

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