Cargando…
144. MSG-15: Pharmacokinetic (PK), Adverse Events (AEs), and Tolerability Data from an Open Label Randomized Clinical Trial (RCT) Comparing Oral Suba-itraconazole (SUBA-ITC) to Conventional Itraconazole (C-ITC) for Treatment of Endemic Mycosis (EM)
BACKGROUND: C-ITC is a drug of choice for non-life-threatening, non-CNS histoplasmosis, blastomycosis, sporotrichosis, coccidioidomycosis and other EM. Oral C-ITC is problematic due to inconsistent absorption often leading to sub-therapeutic serum levels. SUBA-ITC is an FDA approved formulation whic...
Autores principales: | Pappas, Peter G, Spec, Andrej, Miceli, Marisa H, Proia, Laurie, Arauz, Ana Belen, Hayes, Justin, Peinhardt, Alisa, McMullen, Rachel, Moore, Mary K, McGwin, Gerald, Thompson III, George R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778035/ http://dx.doi.org/10.1093/ofid/ofaa439.454 |
Ejemplares similares
-
120. An open-label comparative trial of SUBA-itraconazole (SUBA) versus conventional itraconazole (c-itra) for treatment of proven and probable endemic mycoses (MSG-15): a pharmacokinetic (PK) and adverse Event (AE) analysis
por: Pappas, Peter G, et al.
Publicado: (2021) -
SUBA-Itraconazole for Primary Antifungal Prophylaxis After Allogeneic Hematopoietic Cell Transplantation
por: Lindsay, Julian, et al.
Publicado: (2021) -
1354. Novel Formulation SUBA-Itraconazole in Fed and Fasted Healthy Volunteers: Expanding the Clinical Utility of the Established Mold Active Agent
por: Lindsay, Julian, et al.
Publicado: (2018) -
SUBA: the Arabidopsis Subcellular Database
por: Heazlewood, Joshua L., et al.
Publicado: (2007) -
1139. Novel Formulation SUBA-Itraconazole Prophylaxis in Patients With Hematological Malignancy or Undergoing Allogeneic Stem Cell Transplantation: Follow-up Survival Data
por: Lindsay, Julian, et al.
Publicado: (2018)