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Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization

During developmental progression the genomes of immune cells undergo large-scale changes in chromatin folding. However, insights into signaling pathways and epigenetic control of nuclear architecture remain rudimentary. Here, we found that in activated neutrophils calcium influx rapidly recruited th...

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Detalles Bibliográficos
Autores principales: Zhu, Yina, Denholtz, Matthew, Lu, Hanbin, Murre, Cornelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778268/
https://www.ncbi.nlm.nih.gov/pubmed/33334824
http://dx.doi.org/10.1101/gad.343475.120