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Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization
During developmental progression the genomes of immune cells undergo large-scale changes in chromatin folding. However, insights into signaling pathways and epigenetic control of nuclear architecture remain rudimentary. Here, we found that in activated neutrophils calcium influx rapidly recruited th...
Autores principales: | Zhu, Yina, Denholtz, Matthew, Lu, Hanbin, Murre, Cornelis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778268/ https://www.ncbi.nlm.nih.gov/pubmed/33334824 http://dx.doi.org/10.1101/gad.343475.120 |
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