A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21

The cJun NH(2)-terminal kinase (JNK) signaling pathway is activated by metabolic stress and promotes the development of metabolic syndrome, including hyperglycemia, hyperlipidemia, and insulin resistance. This integrated physiological response involves cross-talk between different organs. Here we de...

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Detalles Bibliográficos
Autores principales: Han, Myoung Sook, Perry, Rachel J., Camporez, João-Paulo, Scherer, Philipp E., Shulman, Gerald I., Gao, Guangping, Davis, Roger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778269/
https://www.ncbi.nlm.nih.gov/pubmed/33334822
http://dx.doi.org/10.1101/gad.344556.120

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