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Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?

BACKGROUND: High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed to construct the continuum of HIV care (CoC) in 2016 in 11 European Union (EU) countries, overall and by key p...

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Autores principales: Vourli, Georgia, Noori, Teymur, Pharris, Anastasia, Porter, Kholoud, Axelsson, Maria, Begovac, Josip, Cazein, Francoise, Costagliola, Dominique, Cowan, Susan, Croxford, Sara, d’Arminio Monforte, Antonella, Delpech, Valerie, Díaz, Asunción, Girardi, Enrico, Gunsenheimer-Bartmeyer, Barbara, Hernando, Victoria, Leierer, Gisela, Lot, Florence, Nunez, Olivier, Obel, Niels, Op de Coul, Eline, Paraskeva, Dimitra, Patrinos, Stavros, Reiss, Peter, Schmid, Daniela, Sonnerborg, Anders, Suligoi, Barbara, Supervie, Virginie, van Sighem, Ard, Zangerle, Robert, Touloumi, Giota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778352/
https://www.ncbi.nlm.nih.gov/pubmed/32960957
http://dx.doi.org/10.1093/cid/ciaa696
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author Vourli, Georgia
Noori, Teymur
Pharris, Anastasia
Porter, Kholoud
Axelsson, Maria
Begovac, Josip
Cazein, Francoise
Costagliola, Dominique
Cowan, Susan
Croxford, Sara
d’Arminio Monforte, Antonella
Delpech, Valerie
Díaz, Asunción
Girardi, Enrico
Gunsenheimer-Bartmeyer, Barbara
Hernando, Victoria
Leierer, Gisela
Lot, Florence
Nunez, Olivier
Obel, Niels
Op de Coul, Eline
Paraskeva, Dimitra
Patrinos, Stavros
Reiss, Peter
Schmid, Daniela
Sonnerborg, Anders
Suligoi, Barbara
Supervie, Virginie
van Sighem, Ard
Zangerle, Robert
Touloumi, Giota
author_facet Vourli, Georgia
Noori, Teymur
Pharris, Anastasia
Porter, Kholoud
Axelsson, Maria
Begovac, Josip
Cazein, Francoise
Costagliola, Dominique
Cowan, Susan
Croxford, Sara
d’Arminio Monforte, Antonella
Delpech, Valerie
Díaz, Asunción
Girardi, Enrico
Gunsenheimer-Bartmeyer, Barbara
Hernando, Victoria
Leierer, Gisela
Lot, Florence
Nunez, Olivier
Obel, Niels
Op de Coul, Eline
Paraskeva, Dimitra
Patrinos, Stavros
Reiss, Peter
Schmid, Daniela
Sonnerborg, Anders
Suligoi, Barbara
Supervie, Virginie
van Sighem, Ard
Zangerle, Robert
Touloumi, Giota
author_sort Vourli, Georgia
collection PubMed
description BACKGROUND: High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed to construct the continuum of HIV care (CoC) in 2016 in 11 European Union (EU) countries, overall and by key population and sex. To estimate progress toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 target, we compared 2016 to 2013 estimates for the same countries, representing 73% of the population in the region. METHODS: A CoC with the following 4 stages was constructed: number of people living with HIV (PLHIV); proportion of PLHIV diagnosed; proportion of those diagnosed who ever initiated ART; and proportion of those ever treated who achieved viral suppression at their last visit. RESULTS: We estimated that 87% of PLHIV were diagnosed; 92% of those diagnosed had ever initiated ART; and 91% of those ever on ART, or 73% of all PLHIV, were virally suppressed. Corresponding figures for men having sex with men were: 86%, 93%, 93%, 74%; for people who inject drugs: 94%, 88%, 85%, 70%; and for heterosexuals: 86%, 92%, 91%, 72%. The proportion suppressed of all PLHIV ranged from 59% to 86% across countries. CONCLUSIONS: The EU is close to the 90-90-90 target and achieved the UNAIDS target of 73% of all PLHIV virally suppressed, significant progress since 2013 when 60% of all PLHIV were virally suppressed. Strengthening of testing programs and treatment support, along with prevention interventions, are needed to achieve HIV epidemic control.
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spelling pubmed-77783522021-01-07 Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress? Vourli, Georgia Noori, Teymur Pharris, Anastasia Porter, Kholoud Axelsson, Maria Begovac, Josip Cazein, Francoise Costagliola, Dominique Cowan, Susan Croxford, Sara d’Arminio Monforte, Antonella Delpech, Valerie Díaz, Asunción Girardi, Enrico Gunsenheimer-Bartmeyer, Barbara Hernando, Victoria Leierer, Gisela Lot, Florence Nunez, Olivier Obel, Niels Op de Coul, Eline Paraskeva, Dimitra Patrinos, Stavros Reiss, Peter Schmid, Daniela Sonnerborg, Anders Suligoi, Barbara Supervie, Virginie van Sighem, Ard Zangerle, Robert Touloumi, Giota Clin Infect Dis Major Articles and Commentaries BACKGROUND: High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed to construct the continuum of HIV care (CoC) in 2016 in 11 European Union (EU) countries, overall and by key population and sex. To estimate progress toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 target, we compared 2016 to 2013 estimates for the same countries, representing 73% of the population in the region. METHODS: A CoC with the following 4 stages was constructed: number of people living with HIV (PLHIV); proportion of PLHIV diagnosed; proportion of those diagnosed who ever initiated ART; and proportion of those ever treated who achieved viral suppression at their last visit. RESULTS: We estimated that 87% of PLHIV were diagnosed; 92% of those diagnosed had ever initiated ART; and 91% of those ever on ART, or 73% of all PLHIV, were virally suppressed. Corresponding figures for men having sex with men were: 86%, 93%, 93%, 74%; for people who inject drugs: 94%, 88%, 85%, 70%; and for heterosexuals: 86%, 92%, 91%, 72%. The proportion suppressed of all PLHIV ranged from 59% to 86% across countries. CONCLUSIONS: The EU is close to the 90-90-90 target and achieved the UNAIDS target of 73% of all PLHIV virally suppressed, significant progress since 2013 when 60% of all PLHIV were virally suppressed. Strengthening of testing programs and treatment support, along with prevention interventions, are needed to achieve HIV epidemic control. Oxford University Press 2020-09-22 /pmc/articles/PMC7778352/ /pubmed/32960957 http://dx.doi.org/10.1093/cid/ciaa696 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Major Articles and Commentaries
Vourli, Georgia
Noori, Teymur
Pharris, Anastasia
Porter, Kholoud
Axelsson, Maria
Begovac, Josip
Cazein, Francoise
Costagliola, Dominique
Cowan, Susan
Croxford, Sara
d’Arminio Monforte, Antonella
Delpech, Valerie
Díaz, Asunción
Girardi, Enrico
Gunsenheimer-Bartmeyer, Barbara
Hernando, Victoria
Leierer, Gisela
Lot, Florence
Nunez, Olivier
Obel, Niels
Op de Coul, Eline
Paraskeva, Dimitra
Patrinos, Stavros
Reiss, Peter
Schmid, Daniela
Sonnerborg, Anders
Suligoi, Barbara
Supervie, Virginie
van Sighem, Ard
Zangerle, Robert
Touloumi, Giota
Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?
title Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?
title_full Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?
title_fullStr Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?
title_full_unstemmed Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?
title_short Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?
title_sort human immunodeficiency virus continuum of care in 11 european union countries at the end of 2016 overall and by key population: have we made progress?
topic Major Articles and Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778352/
https://www.ncbi.nlm.nih.gov/pubmed/32960957
http://dx.doi.org/10.1093/cid/ciaa696
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