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Cotrimoxazole Prophylaxis Increases Resistance Gene Prevalence and α-Diversity but Decreases β-Diversity in the Gut Microbiome of Human Immunodeficiency Virus–Exposed, Uninfected Infants

BACKGROUND: Prophylactic cotrimoxazole treatment is recommended in human immunodeficiency virus (HIV)–exposed, uninfected (HEU) infants, but the effects of this treatment on developing HEU infant gut microbiotas and resistomes are largely undefined. METHODS: We analyzed whole-metagenome sequencing d...

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Detalles Bibliográficos
Autores principales:	D’Souza, Alaric W, Moodley-Govender, Eshia, Berla, Bertram, Kelkar, Tejas, Wang, Bin, Sun, Xiaoqing, Daniels, Brodie, Coutsoudis, Anna, Trehan, Indi, Dantas, Gautam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Major Articles and Commentaries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778358/ https://www.ncbi.nlm.nih.gov/pubmed/31832638 http://dx.doi.org/10.1093/cid/ciz1186

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