A Double-Edged Sword: The Anti-Cancer Effects of Emodin by Inhibiting the Redox-Protective Protein MTH1 and Augmenting ROS in NSCLC

Background: Reactive oxygen species (ROS), playing a two-fold role in tumorigenesis, are responsible for tumor formation and progression through the induction of genome instability and pro-oncogenic signaling. The same ROS is toxic to cancer cells at higher levels, oxidizing free nucleotide precurso...

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Detalles Bibliográficos
Autores principales: Wahi, Divya, Soni, Deepika, Grover, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778552/
https://www.ncbi.nlm.nih.gov/pubmed/33403025
http://dx.doi.org/10.7150/jca.41160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778552/
https://www.ncbi.nlm.nih.gov/pubmed/33403025
http://dx.doi.org/10.7150/jca.41160

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