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Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic

Since the beginning of the pandemic due to the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its related disease, coronavirus disease 2019 (COVID-19), several articles reported negative outcomes in surgery of infected patients. Aim of this study is to report results of patie...

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Autores principales: De Luca, Maurizio, Sartori, Alberto, Vitiello, Antonio, Piatto, Giacomo, Noaro, Giulia, Olmi, Stefano, Foschi, Diego, De Re, Luca, Zappa, Marco, Sarro, Giuliano, Rivolta, Umberto, Giraudo, Giorgio, Borghi, Felice, Pozzo, Gabriele, Sorisio, Vincenzo, Pignata, Giusto, Greco, Paola Antonella, Sisti, Valerio, Campagnaro, Tommaso, Guglielmi, Alfredo, Andreuccetti, Jacopo, Di Leo, Alberto, Lauro, Enrico, Ricci, Francesco, Musella, Mario, Zizzo, Maurizio, Bonacini, Stefano, Podda, Mauro, Pisanu, Adolfo, Coletta, Pietro, Guerrieri, Mario, Caracino, Valerio, Basti, Massimo, Pilone, Vincenzo, Raffaelli, Marco, Oragano, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778576/
https://www.ncbi.nlm.nih.gov/pubmed/33389672
http://dx.doi.org/10.1007/s13304-020-00909-0
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author De Luca, Maurizio
Sartori, Alberto
Vitiello, Antonio
Piatto, Giacomo
Noaro, Giulia
Olmi, Stefano
Foschi, Diego
De Re, Luca
Zappa, Marco
Sarro, Giuliano
Rivolta, Umberto
Giraudo, Giorgio
Borghi, Felice
Pozzo, Gabriele
Sorisio, Vincenzo
Pignata, Giusto
Greco, Paola Antonella
Sisti, Valerio
Campagnaro, Tommaso
Guglielmi, Alfredo
Andreuccetti, Jacopo
Di Leo, Alberto
Lauro, Enrico
Ricci, Francesco
Musella, Mario
Zizzo, Maurizio
Bonacini, Stefano
Podda, Mauro
Pisanu, Adolfo
Coletta, Pietro
Guerrieri, Mario
Caracino, Valerio
Basti, Massimo
Pilone, Vincenzo
Raffaelli, Marco
Oragano, Luigi
author_facet De Luca, Maurizio
Sartori, Alberto
Vitiello, Antonio
Piatto, Giacomo
Noaro, Giulia
Olmi, Stefano
Foschi, Diego
De Re, Luca
Zappa, Marco
Sarro, Giuliano
Rivolta, Umberto
Giraudo, Giorgio
Borghi, Felice
Pozzo, Gabriele
Sorisio, Vincenzo
Pignata, Giusto
Greco, Paola Antonella
Sisti, Valerio
Campagnaro, Tommaso
Guglielmi, Alfredo
Andreuccetti, Jacopo
Di Leo, Alberto
Lauro, Enrico
Ricci, Francesco
Musella, Mario
Zizzo, Maurizio
Bonacini, Stefano
Podda, Mauro
Pisanu, Adolfo
Coletta, Pietro
Guerrieri, Mario
Caracino, Valerio
Basti, Massimo
Pilone, Vincenzo
Raffaelli, Marco
Oragano, Luigi
author_sort De Luca, Maurizio
collection PubMed
description Since the beginning of the pandemic due to the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its related disease, coronavirus disease 2019 (COVID-19), several articles reported negative outcomes in surgery of infected patients. Aim of this study is to report results of patients with COVID-19-positive swab, in the perioperative period after surgery. Data of COVID-19-positive patients undergoing emergent or oncological surgery, were collected in a retrospective, multicenter study, which involved 20 Italian institutions. Collected parameters were age, sex, body mass index, COVID-19-related symptoms, patients’ comorbidities, surgical procedure, personal protection equipment (PPE) used in operating rooms, rate of postoperative infection among healthcare staff and complications, within 30-postoperative days. 68 patients, who underwent surgery, resulted COVID-19-positive in the perioperative period. Symptomatic patients were 63 (92.5%). Fever was the main symptom in 36 (52.9%) patients, followed by dyspnoea (26.5%) and cough (13.2%). We recorded 22 (32%) intensive care unit admissions, 23 (33.8%) postoperative pulmonary complications and 15 (22%) acute respiratory distress syndromes. As regards the ten postoperative deaths (14.7%), 6 cases were related to surgical complications. One surgeon, one scrub nurse and two circulating nurses were infected after surgery due to the lack of specific PPE. We reported less surgery-related pulmonary complications and mortality in Sars-CoV-2-infected patients, than in literature. Emergent and oncological surgery should not be postponed, but it is mandatory to use full PPE, and to adopt preoperative screenings and strategies that mitigate the detrimental effect of pulmonary complications, mostly responsible for mortality.
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spelling pubmed-77785762021-01-04 Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic De Luca, Maurizio Sartori, Alberto Vitiello, Antonio Piatto, Giacomo Noaro, Giulia Olmi, Stefano Foschi, Diego De Re, Luca Zappa, Marco Sarro, Giuliano Rivolta, Umberto Giraudo, Giorgio Borghi, Felice Pozzo, Gabriele Sorisio, Vincenzo Pignata, Giusto Greco, Paola Antonella Sisti, Valerio Campagnaro, Tommaso Guglielmi, Alfredo Andreuccetti, Jacopo Di Leo, Alberto Lauro, Enrico Ricci, Francesco Musella, Mario Zizzo, Maurizio Bonacini, Stefano Podda, Mauro Pisanu, Adolfo Coletta, Pietro Guerrieri, Mario Caracino, Valerio Basti, Massimo Pilone, Vincenzo Raffaelli, Marco Oragano, Luigi Updates Surg Original Article Since the beginning of the pandemic due to the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its related disease, coronavirus disease 2019 (COVID-19), several articles reported negative outcomes in surgery of infected patients. Aim of this study is to report results of patients with COVID-19-positive swab, in the perioperative period after surgery. Data of COVID-19-positive patients undergoing emergent or oncological surgery, were collected in a retrospective, multicenter study, which involved 20 Italian institutions. Collected parameters were age, sex, body mass index, COVID-19-related symptoms, patients’ comorbidities, surgical procedure, personal protection equipment (PPE) used in operating rooms, rate of postoperative infection among healthcare staff and complications, within 30-postoperative days. 68 patients, who underwent surgery, resulted COVID-19-positive in the perioperative period. Symptomatic patients were 63 (92.5%). Fever was the main symptom in 36 (52.9%) patients, followed by dyspnoea (26.5%) and cough (13.2%). We recorded 22 (32%) intensive care unit admissions, 23 (33.8%) postoperative pulmonary complications and 15 (22%) acute respiratory distress syndromes. As regards the ten postoperative deaths (14.7%), 6 cases were related to surgical complications. One surgeon, one scrub nurse and two circulating nurses were infected after surgery due to the lack of specific PPE. We reported less surgery-related pulmonary complications and mortality in Sars-CoV-2-infected patients, than in literature. Emergent and oncological surgery should not be postponed, but it is mandatory to use full PPE, and to adopt preoperative screenings and strategies that mitigate the detrimental effect of pulmonary complications, mostly responsible for mortality. Springer International Publishing 2021-01-03 2021 /pmc/articles/PMC7778576/ /pubmed/33389672 http://dx.doi.org/10.1007/s13304-020-00909-0 Text en © Italian Society of Surgery (SIC) 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
De Luca, Maurizio
Sartori, Alberto
Vitiello, Antonio
Piatto, Giacomo
Noaro, Giulia
Olmi, Stefano
Foschi, Diego
De Re, Luca
Zappa, Marco
Sarro, Giuliano
Rivolta, Umberto
Giraudo, Giorgio
Borghi, Felice
Pozzo, Gabriele
Sorisio, Vincenzo
Pignata, Giusto
Greco, Paola Antonella
Sisti, Valerio
Campagnaro, Tommaso
Guglielmi, Alfredo
Andreuccetti, Jacopo
Di Leo, Alberto
Lauro, Enrico
Ricci, Francesco
Musella, Mario
Zizzo, Maurizio
Bonacini, Stefano
Podda, Mauro
Pisanu, Adolfo
Coletta, Pietro
Guerrieri, Mario
Caracino, Valerio
Basti, Massimo
Pilone, Vincenzo
Raffaelli, Marco
Oragano, Luigi
Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic
title Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic
title_full Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic
title_fullStr Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic
title_full_unstemmed Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic
title_short Complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative SARS-CoV-2 infection: an Italian multicenter study. Teachings of Phase 1 to be brought in Phase 2 pandemic
title_sort complications and mortality in a cohort of patients undergoing emergency and elective surgery with perioperative sars-cov-2 infection: an italian multicenter study. teachings of phase 1 to be brought in phase 2 pandemic
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778576/
https://www.ncbi.nlm.nih.gov/pubmed/33389672
http://dx.doi.org/10.1007/s13304-020-00909-0
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