Imaging atherosclerotic plaques by targeting Galectin-3 and activated macrophages using ((89)Zr)-DFO- Galectin3-F(ab')(2) mAb

Rationale: The high expression of Galectin-3 (Gal3) in macrophages of atherosclerotic plaques suggests its participation in atherosclerosis pathogenesis, and raises the possibility to use it as a target to image disease severity in vivo. Here, we explored the feasibility of tracking atherosclerosis...

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Detalles Bibliográficos
Autores principales: Varasteh, Zohreh, De Rose, Francesco, Mohanta, Sarajo, Li, Yuanfang, Zhang, Xi, Miritsch, Benedikt, Scafetta, Giorgia, Yin, Changjun, Sager, Hendrik B., Glasl, Sarah, Gorpas, Dimitris, Habenicht, Andreas J.R., Ntziachristos, Vasilis, Weber, Wolfgang A., Bartolazzi, Armando, Schwaiger, Markus, D'Alessandria, Calogero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778602/
https://www.ncbi.nlm.nih.gov/pubmed/33408786
http://dx.doi.org/10.7150/thno.50247

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