A general Fc engineering platform for the next generation of antibody therapeutics

Rationale: Fc engineering has become the focus of antibody drug development. The current mutagenesis and in silico protein design methods are confined by the limited throughput and high cost, while the high-throughput phage display and yeast display technologies are not suitable for screening glycos...

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Detalles Bibliográficos
Autores principales: Chen, Da, Zhao, Yingjie, Li, Mingyu, Shang, Hang, Li, Na, Li, Fan, Wang, Wei, Wang, Yuan, Jin, Ruina, Liu, Shiyu, Li, Xun, Gao, Shan, Tian, Yujie, Li, Ruonan, Li, Huanhuan, Zhang, Yongyan, Du, Mingjuan, Cao, Youjia, Zhang, Yan, Li, Xin, Huang, Yi, Hu, Liaoyuan A., Li, Fubin, Zhang, Hongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778609/
https://www.ncbi.nlm.nih.gov/pubmed/33408788
http://dx.doi.org/10.7150/thno.51299

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