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CovalentInDB: a comprehensive database facilitating the discovery of covalent inhibitors

Inhibitors that form covalent bonds with their targets have traditionally been considered highly adventurous due to their potential off-target effects and toxicity concerns. However, with the clinical validation and approval of many covalent inhibitors during the past decade, design and discovery of...

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Detalles Bibliográficos
Autores principales: Du, Hongyan, Gao, Junbo, Weng, Gaoqi, Ding, Junjie, Chai, Xin, Pang, Jinping, Kang, Yu, Li, Dan, Cao, Dongsheng, Hou, Tingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778999/
https://www.ncbi.nlm.nih.gov/pubmed/33068433
http://dx.doi.org/10.1093/nar/gkaa876