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CovalentInDB: a comprehensive database facilitating the discovery of covalent inhibitors
Inhibitors that form covalent bonds with their targets have traditionally been considered highly adventurous due to their potential off-target effects and toxicity concerns. However, with the clinical validation and approval of many covalent inhibitors during the past decade, design and discovery of...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778999/ https://www.ncbi.nlm.nih.gov/pubmed/33068433 http://dx.doi.org/10.1093/nar/gkaa876 |