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dbGuide: a database of functionally validated guide RNAs for genome editing in human and mouse cells

With the technology's accessibility and ease of use, CRISPR has been employed widely in many different organisms and experimental settings. As a result, thousands of publications have used CRISPR to make specific genetic perturbations, establishing in itself a resource of validated guide RNA se...

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Detalles Bibliográficos
Autores principales: Gooden, Alexander A, Evans, Christine N, Sheets, Timothy P, Clapp, Michelle E, Chari, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779039/
https://www.ncbi.nlm.nih.gov/pubmed/33051688
http://dx.doi.org/10.1093/nar/gkaa848