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Inflammatory Myofibroblastic Tumor of Sigmoid Colon: Unusual Cause of Intestinal Obstruction

Inflammatory myofibroblastic tumors (IMFTs) are rare solid mesenchymal tumors frequently noted in children and young adults. It is characterized by variable clinicopathological and etiopathogenetic features. They are commonly reported in the lungs and occurrence in the colon is extremely rare. Here,...

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Autores principales: Chinnakkulam Kandhasamy, Sakthivel, Sundaramurthi, Sudharsanan, Vijayakumar, Chellappa, Goneppanavar, Mangala, Nelamangala Ramakrishnaiah, Vishnu Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779172/
https://www.ncbi.nlm.nih.gov/pubmed/33409054
http://dx.doi.org/10.7759/cureus.11809
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author Chinnakkulam Kandhasamy, Sakthivel
Sundaramurthi, Sudharsanan
Vijayakumar, Chellappa
Goneppanavar, Mangala
Nelamangala Ramakrishnaiah, Vishnu Prasad
author_facet Chinnakkulam Kandhasamy, Sakthivel
Sundaramurthi, Sudharsanan
Vijayakumar, Chellappa
Goneppanavar, Mangala
Nelamangala Ramakrishnaiah, Vishnu Prasad
author_sort Chinnakkulam Kandhasamy, Sakthivel
collection PubMed
description Inflammatory myofibroblastic tumors (IMFTs) are rare solid mesenchymal tumors frequently noted in children and young adults. It is characterized by variable clinicopathological and etiopathogenetic features. They are commonly reported in the lungs and occurrence in the colon is extremely rare. Here, we report a case of IMFT in the sigmoid colon confirmed histopathologically after surgical resection. A 40-year-old lady presented with abdominal pain, vomiting, and constipation for four days. On abdominal examination, there was tenderness in the left iliac fossa region with localized guarding. Contrast-enhanced computed tomography (CECT) showed a sigmoid colonic mass lesion with few enlarged perilesional lymph nodes. Colonoscopy demonstrated circumferential ulceration with irregular margin associated with luminal narrowing noted 55 cm from the anal verge and scope could not negotiate beyond, biopsies were taken. Later, the biopsy came as descriptive in nature. Hence, we proceeded for surgery and intra-operatively we have found there was circumferential thickening in the sigmoid colon for about size 8 cm of which was abutting the left lateral parietal wall. We have done sigmoid colon resection with adequate margins and postoperatively patient did well. Finally, the histopathology report suggested an IMFT sigmoid colon.
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spelling pubmed-77791722021-01-05 Inflammatory Myofibroblastic Tumor of Sigmoid Colon: Unusual Cause of Intestinal Obstruction Chinnakkulam Kandhasamy, Sakthivel Sundaramurthi, Sudharsanan Vijayakumar, Chellappa Goneppanavar, Mangala Nelamangala Ramakrishnaiah, Vishnu Prasad Cureus Pathology Inflammatory myofibroblastic tumors (IMFTs) are rare solid mesenchymal tumors frequently noted in children and young adults. It is characterized by variable clinicopathological and etiopathogenetic features. They are commonly reported in the lungs and occurrence in the colon is extremely rare. Here, we report a case of IMFT in the sigmoid colon confirmed histopathologically after surgical resection. A 40-year-old lady presented with abdominal pain, vomiting, and constipation for four days. On abdominal examination, there was tenderness in the left iliac fossa region with localized guarding. Contrast-enhanced computed tomography (CECT) showed a sigmoid colonic mass lesion with few enlarged perilesional lymph nodes. Colonoscopy demonstrated circumferential ulceration with irregular margin associated with luminal narrowing noted 55 cm from the anal verge and scope could not negotiate beyond, biopsies were taken. Later, the biopsy came as descriptive in nature. Hence, we proceeded for surgery and intra-operatively we have found there was circumferential thickening in the sigmoid colon for about size 8 cm of which was abutting the left lateral parietal wall. We have done sigmoid colon resection with adequate margins and postoperatively patient did well. Finally, the histopathology report suggested an IMFT sigmoid colon. Cureus 2020-11-30 /pmc/articles/PMC7779172/ /pubmed/33409054 http://dx.doi.org/10.7759/cureus.11809 Text en Copyright © 2020, Chinnakkulam Kandhasamy et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Chinnakkulam Kandhasamy, Sakthivel
Sundaramurthi, Sudharsanan
Vijayakumar, Chellappa
Goneppanavar, Mangala
Nelamangala Ramakrishnaiah, Vishnu Prasad
Inflammatory Myofibroblastic Tumor of Sigmoid Colon: Unusual Cause of Intestinal Obstruction
title Inflammatory Myofibroblastic Tumor of Sigmoid Colon: Unusual Cause of Intestinal Obstruction
title_full Inflammatory Myofibroblastic Tumor of Sigmoid Colon: Unusual Cause of Intestinal Obstruction
title_fullStr Inflammatory Myofibroblastic Tumor of Sigmoid Colon: Unusual Cause of Intestinal Obstruction
title_full_unstemmed Inflammatory Myofibroblastic Tumor of Sigmoid Colon: Unusual Cause of Intestinal Obstruction
title_short Inflammatory Myofibroblastic Tumor of Sigmoid Colon: Unusual Cause of Intestinal Obstruction
title_sort inflammatory myofibroblastic tumor of sigmoid colon: unusual cause of intestinal obstruction
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779172/
https://www.ncbi.nlm.nih.gov/pubmed/33409054
http://dx.doi.org/10.7759/cureus.11809
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