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Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver
Glucagon promotes hepatic glucose production, lipolysis and amino acid catabolism. Inhibition of glucagon activity, or glucagon resistance, not only lowers blood glucose levels, but also induces non‐alcoholic fatty liver disease and hyperaminoacidemia.[Image: see text]
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779274/ https://www.ncbi.nlm.nih.gov/pubmed/32506830 http://dx.doi.org/10.1111/jdi.13315 |
| _version_ | 1783631299619061760 |
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| author | Hayashi, Yoshitaka |
| author_facet | Hayashi, Yoshitaka |
| author_sort | Hayashi, Yoshitaka |
| collection | PubMed |
| description | Glucagon promotes hepatic glucose production, lipolysis and amino acid catabolism. Inhibition of glucagon activity, or glucagon resistance, not only lowers blood glucose levels, but also induces non‐alcoholic fatty liver disease and hyperaminoacidemia.[Image: see text] |
| format | Online Article Text |
| id | pubmed-7779274 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-77792742021-01-08 Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver Hayashi, Yoshitaka J Diabetes Investig Commentary Glucagon promotes hepatic glucose production, lipolysis and amino acid catabolism. Inhibition of glucagon activity, or glucagon resistance, not only lowers blood glucose levels, but also induces non‐alcoholic fatty liver disease and hyperaminoacidemia.[Image: see text] John Wiley and Sons Inc. 2020-07-26 2021-01 /pmc/articles/PMC7779274/ /pubmed/32506830 http://dx.doi.org/10.1111/jdi.13315 Text en © 2020 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | Commentary Hayashi, Yoshitaka Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver |
| title | Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver |
| title_full | Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver |
| title_fullStr | Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver |
| title_full_unstemmed | Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver |
| title_short | Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver |
| title_sort | glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in the liver |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779274/ https://www.ncbi.nlm.nih.gov/pubmed/32506830 http://dx.doi.org/10.1111/jdi.13315 |
| work_keys_str_mv | AT hayashiyoshitaka glucagonregulateslipolysisandfattyacidoxidationthroughinositoltriphosphatereceptor1intheliver |