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Repeat partial nephrectomy for recurrence of Von Hippel-Lindau-related renal cell carcinoma in an autotransplanted kidney

Von Hippel-Lindau disease predisposes to develop renal cell carcinoma (RCC). Treatment is frequently challenging due to presence of bilateral tumors and high risk of recurrence. We present the case of a VHL-patient with bilateral recurrence of clear-cell RCC after bilateral partial nephrectomy and a...

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Autores principales: Perri, D., Marchioro, G., Bondonno, G., Maso, G., Porta, C., Volpe, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779319/
https://www.ncbi.nlm.nih.gov/pubmed/33425683
http://dx.doi.org/10.1016/j.eucr.2020.101553
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author Perri, D.
Marchioro, G.
Bondonno, G.
Maso, G.
Porta, C.
Volpe, A.
author_facet Perri, D.
Marchioro, G.
Bondonno, G.
Maso, G.
Porta, C.
Volpe, A.
author_sort Perri, D.
collection PubMed
description Von Hippel-Lindau disease predisposes to develop renal cell carcinoma (RCC). Treatment is frequently challenging due to presence of bilateral tumors and high risk of recurrence. We present the case of a VHL-patient with bilateral recurrence of clear-cell RCC after bilateral partial nephrectomy and autotransplantation on one side. Recurrence on the transplanted kidney was treated with repeat partial nephrectomy with good oncological and functional outcomes. This approach is feasible in centres with wide experience in partial nephrectomy and renal transplantation when minimally invasive tumor ablation is not indicated.
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spelling pubmed-77793192021-01-08 Repeat partial nephrectomy for recurrence of Von Hippel-Lindau-related renal cell carcinoma in an autotransplanted kidney Perri, D. Marchioro, G. Bondonno, G. Maso, G. Porta, C. Volpe, A. Urol Case Rep Oncology Von Hippel-Lindau disease predisposes to develop renal cell carcinoma (RCC). Treatment is frequently challenging due to presence of bilateral tumors and high risk of recurrence. We present the case of a VHL-patient with bilateral recurrence of clear-cell RCC after bilateral partial nephrectomy and autotransplantation on one side. Recurrence on the transplanted kidney was treated with repeat partial nephrectomy with good oncological and functional outcomes. This approach is feasible in centres with wide experience in partial nephrectomy and renal transplantation when minimally invasive tumor ablation is not indicated. Elsevier 2020-12-28 /pmc/articles/PMC7779319/ /pubmed/33425683 http://dx.doi.org/10.1016/j.eucr.2020.101553 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Perri, D.
Marchioro, G.
Bondonno, G.
Maso, G.
Porta, C.
Volpe, A.
Repeat partial nephrectomy for recurrence of Von Hippel-Lindau-related renal cell carcinoma in an autotransplanted kidney
title Repeat partial nephrectomy for recurrence of Von Hippel-Lindau-related renal cell carcinoma in an autotransplanted kidney
title_full Repeat partial nephrectomy for recurrence of Von Hippel-Lindau-related renal cell carcinoma in an autotransplanted kidney
title_fullStr Repeat partial nephrectomy for recurrence of Von Hippel-Lindau-related renal cell carcinoma in an autotransplanted kidney
title_full_unstemmed Repeat partial nephrectomy for recurrence of Von Hippel-Lindau-related renal cell carcinoma in an autotransplanted kidney
title_short Repeat partial nephrectomy for recurrence of Von Hippel-Lindau-related renal cell carcinoma in an autotransplanted kidney
title_sort repeat partial nephrectomy for recurrence of von hippel-lindau-related renal cell carcinoma in an autotransplanted kidney
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779319/
https://www.ncbi.nlm.nih.gov/pubmed/33425683
http://dx.doi.org/10.1016/j.eucr.2020.101553
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