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Mitotic cells can repair DNA double-strand breaks via a homology-directed pathway

The choice of repair pathways of DNA double-strand breaks (DSBs) is dependent upon the cell cycle phases. While homologous recombination repair (HRR) is active between the S and G2 phases, its involvement in mitotic DSB repair has not been examined in detail. In the present study, we developed a new...

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Detalles Bibliográficos
Autores principales:	Sakamoto, Yuki, Kokuta, Tetsuya, Teshigahara, Ai, Iijima, Kenta, Kitao, Hiroyuki, Takata, Minoru, Tauchi, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Fundamental Radiation Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779344/ https://www.ncbi.nlm.nih.gov/pubmed/33009557 http://dx.doi.org/10.1093/jrr/rraa095

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