Candida Endocarditis in Patients with Candidemia: A Single-Center Experience of 14 Cases

A retrospective, single-center analysis of 14 cases of Candida endocarditis (from 355 candidemia cases during the years 2012–2019) revealed a high in-hospital mortality (57.1%), a high proportion of healthcare-associated infections (13/14) and a high treatment preference for echinocandins. Transthor...

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Detalles Bibliográficos
Autores principales: Hitzenbichler, Florian, Joha, Tobias, Simon, Michaela, Grosse, Jirka, Menhart, Karin, Hellwig, Dirk, Camboni, Daniele, Sag, Sabine, Sag, Can Martin, Hanses, Frank, Salzberger, Bernd, Mohr, Arno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779412/
https://www.ncbi.nlm.nih.gov/pubmed/33034836
http://dx.doi.org/10.1007/s11046-020-00492-3
Descripción
Sumario:A retrospective, single-center analysis of 14 cases of Candida endocarditis (from 355 candidemia cases during the years 2012–2019) revealed a high in-hospital mortality (57.1%), a high proportion of healthcare-associated infections (13/14) and a high treatment preference for echinocandins. Transthoracic echocardiography and (18)F-FDG PET/CT had a sensitivity of 54.5% and 57.1%, respectively. Patients were older than previously described and most patients with Candida endocarditis had persistent candidemia for ≥ 3 days despite antifungal therapy. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11046-020-00492-3) contains supplementary material, which is available to authorized users.

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